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ASMTL

GENERAL INFORMATION

Gene name

 ASMTL

Gene description

 Acetylserotonin O-methyltransferase-like

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA003630 , HPA021865
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA003630
HPA021865

GENE INFORMATION

Gene name

 ASMTL

Synonyms

Description

 Acetylserotonin O-methyltransferase-like (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene has an N-terminus that is similar to the multicopy associated filamentation (maf) protein of Bacillus subtilis and to orfE of Escherichia coli, while the C-terminus is similar to N-acetylserotonin O-methyltransferase. This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Chromosome

 X

Cytoband

 p22.33

Chromosome location (bp)

 1403139 - 1453762

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000169093 (version 83.38)

Entrez gene

 8623

UniProt

 O95671 (UniProt - Evidence at protein level)

neXtProt

 NX_O95671

Antibodypedia

 ASMTL antibodies

PROTEIN BROWSER
ASMTL-001
ASMTL-005
ASMTL-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ASMTL-001
ENSP00000370734
ENST00000381333
O95671 [Direct mapping]
N-acetylserotonin O-methyltransferase-like protein
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008150 [biological_process]
GO:0008168 [methyltransferase activity]
GO:0008171 [O-methyltransferase activity]
GO:0032259 [methylation]
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 605 aa
67.2 kDa 		No 0
ASMTL-005
ENSP00000370718
ENST00000381317
O95671 [Direct mapping]
N-acetylserotonin O-methyltransferase-like protein
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008150 [biological_process]
GO:0008168 [methyltransferase activity]
GO:0008171 [O-methyltransferase activity]
GO:0032259 [methylation]
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 621 aa
68.9 kDa 		No 0
ASMTL-201
ENSP00000446410
ENST00000534940
O95671 [Direct mapping]
N-acetylserotonin O-methyltransferase-like protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008150 [biological_process]
GO:0008168 [methyltransferase activity]
GO:0008171 [O-methyltransferase activity]
GO:0032259 [methylation]
Show all
 563 aa
62.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.