Cell atlas - SNUPN - The Human Protein Atlas

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SNUPN

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear membrane

Human cell
	Nuclear membrane

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GENERAL INFORMATION
Gene name	SNUPN
Gene description	Snurportin 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nuclear membrane.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear membrane (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. CAB005004
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nuclear membrane.

Main location

Nuclear membrane (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	CAB005004	A-431	Nuclear membrane
	CAB005004	U-2 OS	Nuclear membrane
	CAB005004	U-251 MG	Nuclear membrane

GENE INFORMATION
Gene name	SNUPN (HGNC Symbol)
Synonyms	RNUT1, SNURPORTIN-1, Snurportin1
Description	Snurportin 1 (HGNC Symbol)
Entrez gene summary	The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Chromosome	15
Cytoband	q24.2
Chromosome location (bp)	75598083 - 75626469
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169371 (version 83.38)
Entrez gene	10073
UniProt	O95149 (UniProt - Evidence at protein level)
neXtProt	NX_O95149
Antibodypedia	SNUPN antibodies

PROTEIN BROWSER

SNUPN-001	SNUPN-002	SNUPN-003	SNUPN-004	SNUPN-005	SNUPN-006	SNUPN-007	SNUPN-008	SNUPN-009	SNUPN-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SNUPN-001 ENSP00000309831 ENST00000308588	O95149 [Direct mapping] Snurportin-1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000339 [RNA cap binding] GO:0000387 [spliceosomal snRNP assembly] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005643 [nuclear pore] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006606 [protein import into nucleus] GO:0008565 [protein transporter activity] GO:0010467 [gene expression] GO:0034660 [ncRNA metabolic process] GO:0061015 [snRNA import into nucleus] GO:0070062 [extracellular exosome] Show all	360 aa 41.1 kDa	No	0
SNUPN-002 ENSP00000454852 ENST00000564644	O95149 [Direct mapping] Snurportin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000339 [RNA cap binding] GO:0000387 [spliceosomal snRNP assembly] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005643 [nuclear pore] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006606 [protein import into nucleus] GO:0008565 [protein transporter activity] GO:0010467 [gene expression] GO:0034660 [ncRNA metabolic process] GO:0061015 [snRNA import into nucleus] GO:0070062 [extracellular exosome] Show all	360 aa 41.1 kDa	No	0
SNUPN-003 ENSP00000458053 ENST00000564675	O95149 [Direct mapping] Snurportin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000339 [RNA cap binding] GO:0000387 [spliceosomal snRNP assembly] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005643 [nuclear pore] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006606 [protein import into nucleus] GO:0008565 [protein transporter activity] GO:0010467 [gene expression] GO:0034660 [ncRNA metabolic process] GO:0061015 [snRNA import into nucleus] GO:0070062 [extracellular exosome] Show all	360 aa 41.1 kDa	No	0
SNUPN-004 ENSP00000456224 ENST00000567134	O95149 [Direct mapping] Snurportin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000339 [RNA cap binding] GO:0000387 [spliceosomal snRNP assembly] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005643 [nuclear pore] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006606 [protein import into nucleus] GO:0008565 [protein transporter activity] GO:0010467 [gene expression] GO:0034660 [ncRNA metabolic process] GO:0061015 [snRNA import into nucleus] GO:0070062 [extracellular exosome] Show all	360 aa 41.1 kDa	No	0
SNUPN-005 ENSP00000456742 ENST00000564086	H3BSK1 [Direct mapping] Snurportin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006606 [protein import into nucleus] GO:0008565 [protein transporter activity] Show all	136 aa 15.7 kDa	No	0
SNUPN-006 ENSP00000456260 ENST00000569817	H3BRI5 [Direct mapping] Snurportin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006606 [protein import into nucleus] GO:0008565 [protein transporter activity] Show all	210 aa 24.4 kDa	No	0
SNUPN-007 ENSP00000455649 ENST00000563875		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		2 aa 0.3 kDa	No	0
SNUPN-008 ENSP00000455894 ENST00000563793	H3BQR0 [Direct mapping] Snurportin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006606 [protein import into nucleus] GO:0008565 [protein transporter activity] Show all	63 aa 7.3 kDa	No	0
SNUPN-009 ENSP00000457093 ENST00000568162	H3BTA6 [Direct mapping] Snurportin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006606 [protein import into nucleus] GO:0008565 [protein transporter activity] Show all	100 aa 11.7 kDa	No	0
SNUPN-010 ENSP00000457562 ENST00000568078	H3BUB4 [Direct mapping] Snurportin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		200 aa 23.1 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.