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GKN1

GENERAL INFORMATION

Gene name

 GKN1

Gene description

 Gastrokine 1

Protein class

 Plasma proteins
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (stomach)
GTEx:Tissue enriched (stomach)
FANTOM5:Group enriched (placenta, urinary bladder)

Protein evidence

 Evidence at protein level

Protein expression

 Selective cytoplasmic expression in stomach

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA047684
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (stomach)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (stomach)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (placenta, urinary bladder)

GENE INFORMATION

Gene name

 GKN1 (HGNC Symbol)

Synonyms

 AMP18, BRICD1, CA11

Description

 Gastrokine 1 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 p13.3

Chromosome location (bp)

 68974573 - 68980974

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000169605 (version 83.38)

Entrez gene

 56287

UniProt

 Q9NS71 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9NS71

Antibodypedia

 GKN1 antibodies

PROTEIN BROWSER
GKN1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GKN1-001
ENSP00000367172
ENST00000377938
Q9NS71 [Direct mapping]
Gastrokine-1
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003674 [molecular_function]
GO:0005575 [cellular_component]
GO:0005576 [extracellular region]
GO:0007586 [digestion]
GO:0051781 [positive regulation of cell division]
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 199 aa
22 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.