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Several cases of urothelial cancers, squamous and basal cell carcinomas along with a few cases of non-Hodgkins lymphomas and ovarian cancers showed moderate to strong cytoplasmic positivity. Remaining cancers were negative.
GENE INFORMATION
Gene name
RAC3
Synonyms
Description
Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]