Cell atlas - FRMPD4 - The Human Protein Atlas

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FRMPD4

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	FRMPD4
Gene description	FERM and PDZ domain containing 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (U-2197, U-266/70, LHCN-M2)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-2197, U-266/70, LHCN-M2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	FRMPD4 (HGNC Symbol)
Synonyms	KIAA0316, PDZD10, PDZK10
Description	FERM and PDZ domain containing 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission. [provided by RefSeq, Jan 2010]
Chromosome	X
Cytoband	p22.2
Chromosome location (bp)	12138466 - 12724523
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169933 (version 83.38)
Entrez gene	9758
UniProt	Q14CM0 (UniProt - Evidence at protein level)
neXtProt	NX_Q14CM0
Antibodypedia	FRMPD4 antibodies

PROTEIN BROWSER

FRMPD4-001	FRMPD4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FRMPD4-001 ENSP00000370057 ENST00000380682	Q14CM0 [Direct mapping] FERM and PDZ domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding] GO:0005856 [cytoskeleton] GO:0043197 [dendritic spine] GO:0051835 [positive regulation of synapse structural plasticity] Show all	1322 aa 144.4 kDa	No	0
FRMPD4-201 ENSP00000482182 ENST00000616992	A0A087WYX8 [Direct mapping] FERM and PDZ domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005856 [cytoskeleton] Show all	1282 aa 140 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.