Tissue expression of CNTROB - Summary - The Human Protein Atlas

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CNTROB

TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CNTROB
Gene description	Centrobin, centrosomal BRCA2 interacting protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in all cell types.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 4 antibodies. HPA023319 , HPA023320 , HPA023321 , HPA023325
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	CNTROB (HGNC Symbol)
Synonyms	LIP8, PP1221
Description	Centrobin, centrosomal BRCA2 interacting protein (HGNC Symbol)
Entrez gene summary	This gene encodes a centrosomal protein that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Chromosome	17
Cytoband	p13.1
Chromosome location (bp)	7932101 - 7949918
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170037 (version 83.38)
Entrez gene	116840
UniProt	Q8N137 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N137
Antibodypedia	CNTROB antibodies

PROTEIN BROWSER

CNTROB-001	CNTROB-002	CNTROB-003	CNTROB-007	CNTROB-008	CNTROB-009	CNTROB-010	CNTROB-016

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CNTROB-001 ENSP00000369614 ENST00000380262	Q8N137 [Direct mapping] Centrobin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005814 [centriole] GO:0007099 [centriole replication] GO:0019904 [protein domain specific binding] GO:0051299 [centrosome separation] GO:1902410 [mitotic cytokinetic process] Show all	925 aa 103.8 kDa	No	0
CNTROB-002 ENSP00000456335 ENST00000563694	Q8N137 [Direct mapping] Centrobin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005814 [centriole] GO:0007099 [centriole replication] GO:0019904 [protein domain specific binding] GO:0051299 [centrosome separation] GO:1902410 [mitotic cytokinetic process] Show all	903 aa 101.3 kDa	No	0
CNTROB-003 ENSP00000454840 ENST00000565740	Q8N137 [Direct mapping] Centrobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005814 [centriole] GO:0007099 [centriole replication] GO:0019904 [protein domain specific binding] GO:0051299 [centrosome separation] GO:1902410 [mitotic cytokinetic process] Show all	904 aa 101.4 kDa	No	0
CNTROB-007 ENSP00000459246 ENST00000576538	I3L1Z8 [Direct mapping] Centrobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005813 [centrosome] Show all	198 aa 21.6 kDa	No	0
CNTROB-008 ENSP00000460583 ENST00000570782	I3L3N2 [Direct mapping] Centrobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		14 aa 1.3 kDa	No	0
CNTROB-009 ENSP00000461000 ENST00000570784	I3L465 [Direct mapping] Centrobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		77 aa 8.1 kDa	No	0
CNTROB-010 ENSP00000458696 ENST00000575408	I3L1B0 [Direct mapping] Centrobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		199 aa 22.7 kDa	No	0
CNTROB-016 ENSP00000458251 ENST00000576536	I3L0P9 [Direct mapping] Centrobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		187 aa 20.2 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.