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Most cancer tissues showed moderate cytoplasmic and nuclear positivity. Hepatocellular carcinomas and occasional colorectal cancers displayed strong immunoreactivity. Many lymphomas and renal cell carcinomas were weakly stained or negative.
Cancer tissues showed weak to moderate cytoplasmic positivity with additional nuclear staining in several cases. Occasional cases of gliomas and a single case each of colorectal, endometrial, renal, stomach and pancreatic cancers displayed strong positivity. Lymphomas were negative.
A majority of cancer tissues showed weak to moderate cytoplasmic and/or nuclear positivity. Few cases of cholangiocarcinomas exhibited strong immunoreactivity. Lymphomas, carcinoid and testicular cancers were in general negative.
Most cancer tissues showed weak to moderate cytoplasmic positivity with additional membranous or nuclear staining in few cases. Lymphomas along with several lung, cervical, urothelial and renal cancers were negative.
A single case of duct carcinoma of breast showed moderate nuclear staining. Occasional cases of cervix cancers exhibited moderate to strong positivity. Few cases of endometrial cancers and occasional cases of ovarian cancers displayed moderate cytoplasmic and nuclear immunoreactivity. A single case of seminoma showed moderate cytoplasmic staining. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
FAM153A (HGNC Symbol)
Synonyms
NY-REN-7
Description
Family with sequence similarity 153, member A (HGNC Symbol)