Cell atlas - ACYP2 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ACYP2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	ACYP2
Gene description	Acylphosphatase 2, muscle type
Protein class	Enzymes Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA035301
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA035301	A-431	Nucleoplasm
	HPA035301	U-2 OS	Nucleoplasm
	HPA035301	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	ACYP2
Synonyms
Description	Acylphosphatase 2, muscle type (HGNC Symbol)
Entrez gene summary	Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	p16.2
Chromosome location (bp)	53970838 - 54305300
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170634 (version 83.38)
Entrez gene	98
UniProt	P14621 (UniProt - Evidence at protein level)
neXtProt	NX_P14621
Antibodypedia	ACYP2 antibodies

PROTEIN BROWSER

ACYP2-001	ACYP2-002	ACYP2-003	ACYP2-006	ACYP2-007	ACYP2-008	ACYP2-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACYP2-001 ENSP00000378161 ENST00000394666	P14621 [Direct mapping] Acylphosphatase-2 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003998 [acylphosphatase activity] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0006796 [phosphate-containing compound metabolic process] Show all	99 aa 11.1 kDa	No	0
ACYP2-002 ENSP00000306448 ENST00000303536	F8WA34 [Direct mapping] Acylphosphatase Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003998 [acylphosphatase activity] GO:0008152 [metabolic process] Show all	98 aa 10.3 kDa	Yes	0
ACYP2-003 ENSP00000385674 ENST00000406041	E9PF46 [Direct mapping] Acylphosphatase Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003998 [acylphosphatase activity] GO:0008152 [metabolic process] Show all	97 aa 10.3 kDa	Yes	0
ACYP2-006 ENSP00000475986 ENST00000607452	U3KQL2 [Direct mapping] Acylphosphatase-2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003998 [acylphosphatase activity] GO:0008152 [metabolic process] Show all	172 aa 19.6 kDa	No	0
ACYP2-007 ENSP00000475658 ENST00000422521	U3KQ94 [Direct mapping] Acylphosphatase-2; HCG2040114, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		116 aa 13.3 kDa	No	0
ACYP2-008 ENSP00000475424 ENST00000606082	U3KQ09 [Direct mapping] Acylphosphatase-2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		40 aa 4.8 kDa	No	0
ACYP2-010 ENSP00000475333 ENST00000606865	U3KPX8 [Direct mapping] Acylphosphatase-2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003998 [acylphosphatase activity] GO:0008152 [metabolic process] Show all	83 aa 9.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.