Tissue expression of ATF7 - Summary - The Human Protein Atlas

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ATF7

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ATF7
Gene description	Activating transcription factor 7
Protein class	Predicted intracellular proteins Predicted membrane proteins Transcription factors
Predicted localization	Intracellular,Membrane
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in several different tissue types, including cells in stroma.

DATA RELIABILITY
Data reliability description	Caution, targets protein from more than one gene. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA003384
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ATF7 (HGNC Symbol)
Synonyms	ATFA
Description	Activating transcription factor 7 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q13.13
Chromosome location (bp)	53507856 - 53626410
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170653 (version 83.38)
Entrez gene	11016
UniProt	P17544 (UniProt - Evidence at protein level)
neXtProt	NX_P17544
Antibodypedia	ATF7 antibodies

PROTEIN BROWSER

ATF7-001	ATF7-002	ATF7-005	ATF7-006	ATF7-007	ATF7-009	ATF7-010	ATF7-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATF7-001 ENSP00000399465 ENST00000420353	P17544 [Direct mapping] Cyclic AMP-dependent transcription factor ATF-7 Show all	Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0016032 [viral process] GO:0019899 [enzyme binding] GO:0034399 [nuclear periphery] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] GO:0051019 [mitogen-activated protein kinase binding] Show all	483 aa 51.8 kDa	No	0
ATF7-002 ENSP00000465192 ENST00000591397	P17544 [Direct mapping] Cyclic AMP-dependent transcription factor ATF-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Transcription factors Basic domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0016032 [viral process] GO:0019899 [enzyme binding] GO:0034399 [nuclear periphery] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] GO:0051019 [mitogen-activated protein kinase binding] Show all	117 aa 13.3 kDa	No	1
ATF7-005 ENSP00000449817 ENST00000551480	F8VWG7 [Direct mapping] Cyclic AMP-dependent transcription factor ATF-7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		78 aa 8.3 kDa	No	0
ATF7-006 ENSP00000387406 ENST00000456903	P17544 [Direct mapping] Cyclic AMP-dependent transcription factor ATF-7 Show all	Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0016032 [viral process] GO:0019899 [enzyme binding] GO:0034399 [nuclear periphery] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] GO:0051019 [mitogen-activated protein kinase binding] Show all	483 aa 51.8 kDa	No	0
ATF7-007 ENSP00000449938 ENST00000548446	P17544 [Direct mapping] Cyclic AMP-dependent transcription factor ATF-7 Show all	Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0016032 [viral process] GO:0019899 [enzyme binding] GO:0034399 [nuclear periphery] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] GO:0051019 [mitogen-activated protein kinase binding] Show all	494 aa 53 kDa	No	0
ATF7-009 ENSP00000456858 ENST00000548118	P17544 [Direct mapping] Cyclic AMP-dependent transcription factor ATF-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Transcription factors Basic domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0016032 [viral process] GO:0019899 [enzyme binding] GO:0034399 [nuclear periphery] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] GO:0051019 [mitogen-activated protein kinase binding] Show all	117 aa 13.3 kDa	No	1
ATF7-010 ENSP00000465850 ENST00000588232	K7EKZ7 [Direct mapping] Cyclic AMP-dependent transcription factor ATF-7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		79 aa 8.4 kDa	No	0
ATF7-011 ENSP00000468623 ENST00000588078	K7ESA4 [Direct mapping] Cyclic AMP-dependent transcription factor ATF-7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	163 aa 17.8 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.