Fields »
ABOUT
HELP
BLOG
MURC

GENERAL INFORMATION

Gene name

 MURC

Gene description

 Muscle-related coiled-coil protein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (heart muscle, skeletal muscle)
GTEx:Group enriched (heart muscle, skeletal muscle)
FANTOM5:Tissue enriched (skeletal muscle)

Protein evidence

 Evidence at protein level

Protein expression

 Highly specific expression in membranes of striated muscle.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 3 antibodies.
HPA020973 , HPA020987 , HPA021021
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (heart muscle, skeletal muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (heart muscle, skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)

GENE INFORMATION

Gene name

 MURC (HGNC Symbol)

Synonyms

 cavin-4, CAVIN4

Description

 Muscle-related coiled-coil protein (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein containing two coiled-coil regions. The encoded protein promotes Rho/ROCK (Rho-kinase) signaling in cardiac muscles cells, and may facilitate myofibrillar organization. [provided by RefSeq, Jun 2013]

Chromosome

 9

Cytoband

 q31.1

Chromosome location (bp)

 100578079 - 100587906

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000170681 (version 83.38)

Entrez gene

 347273

UniProt

 Q5BKX8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5BKX8

Antibodypedia

 MURC antibodies

PROTEIN BROWSER
MURC-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MURC-001
ENSP00000418668
ENST00000307584
Q5BKX8 [Direct mapping]
Muscle-related coiled-coil protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007517 [muscle organ development]
GO:0010468 [regulation of gene expression]
GO:0030154 [cell differentiation]
Show all
 364 aa
41.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.