Expression of DYDC1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

DYDC1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	DYDC1
Gene description	DPY30 domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (endometrial cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 2 antibodies. HPA037790 , HPA037791
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (endometrial cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA037790	HPA037791

GENE INFORMATION
Gene name	DYDC1 (HGNC Symbol)
Synonyms	bA36D19.5, DPY30D1
Description	DPY30 domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of proteins that contains a DPY30 domain. The encoded protein is involved in acrosome formation during spermatid development. This gene locus overlaps with a closely related gene on the opposite strand. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Chromosome	10
Cytoband	q23.1
Chromosome location (bp)	80336105 - 80356755
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170788 (version 83.38)
Entrez gene	143241
UniProt	Q8WWB3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WWB3
Antibodypedia	DYDC1 antibodies

PROTEIN BROWSER

DYDC1-001	DYDC1-002	DYDC1-003	DYDC1-004	DYDC1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DYDC1-001 ENSP00000361278 ENST00000372204	Q8WWB3 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.9 kDa	No	0
DYDC1-002 ENSP00000361276 ENST00000372202	Q8WWB3 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.9 kDa	No	0
DYDC1-003 ENSP00000414798 ENST00000454362	X1WI33 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all		153 aa 18.1 kDa	No	0
DYDC1-004 ENSP00000388160 ENST00000453477	A0A0A0MSH3 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all		80 aa 9.6 kDa	No	0
DYDC1-201 ENSP00000402890 ENST00000421924	Q8WWB3 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.