Tissue expression of DYDC1 - Summary - The Human Protein Atlas

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DYDC1

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	DYDC1
Gene description	DPY30 domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 2 antibodies. HPA037790 , HPA037791
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	DYDC1 (HGNC Symbol)
Synonyms	bA36D19.5, DPY30D1
Description	DPY30 domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of proteins that contains a DPY30 domain. The encoded protein is involved in acrosome formation during spermatid development. This gene locus overlaps with a closely related gene on the opposite strand. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Chromosome	10
Cytoband	q23.1
Chromosome location (bp)	80336105 - 80356755
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170788 (version 83.38)
Entrez gene	143241
UniProt	Q8WWB3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WWB3
Antibodypedia	DYDC1 antibodies

PROTEIN BROWSER

DYDC1-001	DYDC1-002	DYDC1-003	DYDC1-004	DYDC1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DYDC1-001 ENSP00000361278 ENST00000372204	Q8WWB3 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.9 kDa	No	0
DYDC1-002 ENSP00000361276 ENST00000372202	Q8WWB3 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.9 kDa	No	0
DYDC1-003 ENSP00000414798 ENST00000454362	X1WI33 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all		153 aa 18.1 kDa	No	0
DYDC1-004 ENSP00000388160 ENST00000453477	A0A0A0MSH3 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all		80 aa 9.6 kDa	No	0
DYDC1-201 ENSP00000402890 ENST00000421924	Q8WWB3 [Direct mapping] DPY30 domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.