Tissue expression of NUDT6 - Summary - The Human Protein Atlas

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NUDT6

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	NUDT6
Gene description	Nudix (nucleoside diphosphate linked moiety X)-type motif 6
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Uncertain based on 2 antibodies. HPA039202 , HPA066115
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

N/A

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	NUDT6 (HGNC Symbol)
Synonyms	FGF-AS, FGF2AS, gfg, gfg-1
Description	Nudix (nucleoside diphosphate linked moiety X)-type motif 6 (HGNC Symbol)
Entrez gene summary	This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Chromosome	4
Cytoband	q28.1
Chromosome location (bp)	122888697 - 122922968
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170917 (version 83.38)
Entrez gene	11162
UniProt	P53370 (UniProt - Evidence at protein level)
neXtProt	NX_P53370
Antibodypedia	NUDT6 antibodies

PROTEIN BROWSER

NUDT6-001	NUDT6-002	NUDT6-004	NUDT6-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NUDT6-001 ENSP00000306070 ENST00000304430	P53370 [Direct mapping] Nucleoside diphosphate-linked moiety X motif 6 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0008083 [growth factor activity] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	316 aa 35.7 kDa	No	0
NUDT6-002 ENSP00000344011 ENST00000339154	P53370 [Direct mapping] Nucleoside diphosphate-linked moiety X motif 6 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0008083 [growth factor activity] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	147 aa 17.1 kDa	No	0
NUDT6-004 ENSP00000423745 ENST00000510735	H0Y9C0 [Direct mapping] Nucleoside diphosphate-linked moiety X motif 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		50 aa 5.5 kDa	No	0
NUDT6-007 ENSP00000424117 ENST00000502270	P53370 [Direct mapping] Nucleoside diphosphate-linked moiety X motif 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0008083 [growth factor activity] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	147 aa 17.1 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.