Cell atlas - KRT20 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

KRT20

premium

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	KRT20
Gene description	Keratin 20, type I
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Cell line enhanced (RT4, BEWO)
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA024684
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RT4, BEWO) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA024684	A-431	Cytosol
	HPA024684	U-2 OS	Cytosol
	HPA024684	U-251 MG	Cytosol

GENE INFORMATION
Gene name	KRT20 (HGNC Symbol)
Synonyms	CK20, K20, MGC35423
Description	Keratin 20, type I (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q21.2
Chromosome location (bp)	40875941 - 40885227
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000171431 (version 83.38)
Entrez gene	54474
UniProt	P35900 (UniProt - Evidence at protein level)
neXtProt	NX_P35900
Antibodypedia	KRT20 antibodies

PROTEIN BROWSER

KRT20-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KRT20-001 ENSP00000167588 ENST00000167588	P35900 [Direct mapping] Keratin, type I cytoskeletal 20 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005200 [structural constituent of cytoskeleton] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005882 [intermediate filament] GO:0006915 [apoptotic process] GO:0033554 [cellular response to stress] GO:0045109 [intermediate filament organization] GO:0050708 [regulation of protein secretion] Show all	424 aa 48.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.