Cell atlas - GTPBP2 - The Human Protein Atlas

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GTPBP2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Vesicles

Human cell
	Vesicles

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GENERAL INFORMATION
Gene name	GTPBP2
Gene description	GTP binding protein 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to vesicles.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (validated)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA031418 , HPA031419
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ASSAYS

RNA expression

Human cells

Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to vesicles.

Main location

Vesicles (validated)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA031418	A-431	No staining
HPA031418	HeLa	Vesicles
HPA031419	A-431	Vesicles
HPA031419	U-2 OS	Vesicles

MOUSE CELLS

Main location

Not available

Mouse gene

ENSMUSG00000023952 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA031418	NIH 3T3	No staining

GENE INFORMATION
Gene name	GTPBP2
Synonyms
Description	GTP binding protein 2 (HGNC Symbol)
Entrez gene summary	GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wide range of biologic activities.[supplied by OMIM, Jan 2003]
Chromosome	6
Cytoband	p21.1
Chromosome location (bp)	43605316 - 43629162
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172432 (version 83.38)
Entrez gene	54676
UniProt	Q9BX10 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BX10
Antibodypedia	GTPBP2 antibodies

PROTEIN BROWSER

GTPBP2-004	GTPBP2-005	GTPBP2-006	GTPBP2-009	GTPBP2-011	GTPBP2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GTPBP2-004 ENSP00000392944 ENST00000419497	H0Y4M5 [Direct mapping] GTP-binding protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		153 aa 16.6 kDa	No	0
GTPBP2-005 ENSP00000398905 ENST00000432918	H0Y5J1 [Direct mapping] GTP-binding protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		154 aa 16.7 kDa	No	0
GTPBP2-006 ENSP00000410676 ENST00000452781	X6RJ09 [Direct mapping] GTP-binding protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		227 aa 24.8 kDa	No	0
GTPBP2-009 ENSP00000411358 ENST00000442748	H0Y7A5 [Direct mapping] GTP-binding protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0008152 [metabolic process] Show all	316 aa 35.2 kDa	No	0
GTPBP2-011 ENSP00000303997 ENST00000307126	Q9BX10 [Direct mapping] GTP-binding protein 2 A0A024RD30 [Target identity:100%; Query identity:100%] GTP binding protein 2, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0006413 [translational initiation] GO:0008150 [biological_process] GO:0043231 [intracellular membrane-bounded organelle] Show all	602 aa 65.8 kDa	No	0
GTPBP2-201 ENSP00000304893 ENST00000307114	Q9BX10 [Direct mapping] GTP-binding protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0006413 [translational initiation] GO:0008150 [biological_process] GO:0043231 [intracellular membrane-bounded organelle] Show all	514 aa 56.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.