Tissue expression of ACOT12 - Summary - The Human Protein Atlas

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ACOT12

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ACOT12
Gene description	Acyl-CoA thioesterase 12
Protein class	Enzymes Predicted intracellular proteins Transporters
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (liver)
GTEx:	Tissue enriched (liver)
FANTOM5:	Tissue enriched (liver)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA037723 , HPA037724
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (liver)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (liver)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (liver)

GENE INFORMATION
Gene name	ACOT12 (HGNC Symbol)
Synonyms	Cach, STARD15, THEAL
Description	Acyl-CoA thioesterase 12 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q14.1
Chromosome location (bp)	81330005 - 81394179
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172497 (version 83.38)
Entrez gene	134526
UniProt	Q8WYK0 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WYK0
Antibodypedia	ACOT12 antibodies

PROTEIN BROWSER

ACOT12-001	ACOT12-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACOT12-001 ENSP00000303246 ENST00000307624	Q8WYK0 [Direct mapping] Acyl-coenzyme A thioesterase 12 Show all	Enzymes ENZYME proteins Hydrolases Transporters Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003986 [acetyl-CoA hydrolase activity] GO:0005524 [ATP binding] GO:0005829 [cytosol] GO:0006084 [acetyl-CoA metabolic process] GO:0006090 [pyruvate metabolic process] GO:0006631 [fatty acid metabolic process] GO:0006637 [acyl-CoA metabolic process] GO:0008289 [lipid binding] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	555 aa 62 kDa	No	0
ACOT12-002 ENSP00000421628 ENST00000513751	Q8WYK0 [Direct mapping] Acyl-coenzyme A thioesterase 12 Show all	Enzymes ENZYME proteins Hydrolases Transporters Predicted intracellular proteins Show all	GO:0003986 [acetyl-CoA hydrolase activity] GO:0005829 [cytosol] GO:0006090 [pyruvate metabolic process] GO:0006631 [fatty acid metabolic process] GO:0006637 [acyl-CoA metabolic process] GO:0008289 [lipid binding] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	167 aa 18.3 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.