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CTSW

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GENERAL INFORMATION

Gene name

 CTSW

Gene description

 Cathepsin W

Protein class

 Enzymes
Plasma proteins
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Group enriched (NB-4, HEL)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (NB-4, HEL)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 CTSW

Synonyms

Description

 Cathepsin W (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008]

Chromosome

 11

Cytoband

 q13.1

Chromosome location (bp)

 65879809 - 65883741

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000172543 (version 83.38)

Entrez gene

 1521

UniProt

 P56202 (UniProt - Evidence at protein level)

neXtProt

 NX_P56202

Antibodypedia

 CTSW antibodies

PROTEIN BROWSER
CTSW-001
CTSW-002
CTSW-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CTSW-001
ENSP00000311300
ENST00000307886
P56202 [Direct mapping]
Cathepsin W
Show all
Enzymes
   Peptidases
   Cysteine-type peptidases
   SCAMPI predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004197 [cysteine-type endopeptidase activity]
GO:0005615 [extracellular space]
GO:0005764 [lysosome]
GO:0006508 [proteolysis]
GO:0006955 [immune response]
GO:0008234 [cysteine-type peptidase activity]
GO:0016020 [membrane]
GO:0051603 [proteolysis involved in cellular protein catabolic process]
Show all
 376 aa
42.1 kDa 		Yes 0
CTSW-002
ENSP00000436568
ENST00000528419
E9PI30 [Direct mapping]
Cathepsin W
Show all
   SCAMPI predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004197 [cysteine-type endopeptidase activity]
GO:0005615 [extracellular space]
GO:0005764 [lysosome]
GO:0006508 [proteolysis]
GO:0008234 [cysteine-type peptidase activity]
GO:0051603 [proteolysis involved in cellular protein catabolic process]
Show all
 364 aa
40.8 kDa 		Yes 0
CTSW-004
ENSP00000434267
ENST00000526034
H0YDT2 [Direct mapping]
Cathepsin W
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004197 [cysteine-type endopeptidase activity]
GO:0005615 [extracellular space]
GO:0005764 [lysosome]
GO:0006508 [proteolysis]
GO:0008234 [cysteine-type peptidase activity]
GO:0051603 [proteolysis involved in cellular protein catabolic process]
Show all
 211 aa
23.7 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.