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ABLIM3

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GENERAL INFORMATION

Gene name

 ABLIM3

Gene description

 Actin binding LIM protein family, member 3

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the plasma membrane. In addition localized to the cell junctions & nucleoplasm.

RNA cell category

 Cell line enhanced (TIME, PC-3)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Plasma membrane (approved)

Additional location

 In addition localized to the Nucleoplasm (approved), Cell Junctions (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA003245
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (TIME, PC-3)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the plasma membrane. In addition localized to the cell junctions & nucleoplasm.

Main location

 Plasma membrane (approved)

Additional location

 Nucleoplasm (approved), Cell Junctions (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA003245 PC-3 Nucleoplasm
Plasma membrane
HPA003245 U-251 MG Cell Junctions

GENE INFORMATION

Gene name

 ABLIM3 (HGNC Symbol)

Synonyms

 KIAA0843

Description

 Actin binding LIM protein family, member 3 (HGNC Symbol)

Entrez gene summary

 The LIM domain is a double zinc finger structure that promotes protein-protein interactions. LIM domain proteins, such as ABLIM3, play roles in embryonic development, cell lineage determination, and cancer (Krupp et al., 2006 [PubMed 16328021]).[supplied by OMIM, Mar 2008]

Chromosome

 5

Cytoband

 q32

Chromosome location (bp)

 149141483 - 149260542

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000173210 (version 83.38)

Entrez gene

 22885

UniProt

 O94929 (UniProt - Evidence at protein level)

neXtProt

 NX_O94929

Antibodypedia

 ABLIM3 antibodies

PROTEIN BROWSER
ABLIM3-001
ABLIM3-002
ABLIM3-004
ABLIM3-005
ABLIM3-006
ABLIM3-011
ABLIM3-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ABLIM3-001
ENSP00000310309
ENST00000309868
O94929 [Direct mapping]
Actin-binding LIM protein 3
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001725 [stress fiber]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0030027 [lamellipodium]
GO:0030032 [lamellipodium assembly]
GO:0030036 [actin cytoskeleton organization]
GO:0042384 [cilium assembly]
GO:1903955 [positive regulation of protein targeting to mitochondrion]
Show all
 683 aa
77.8 kDa 		No 0
ABLIM3-002
ENSP00000425394
ENST00000506113
O94929 [Direct mapping]
Actin-binding LIM protein 3
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001725 [stress fiber]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0030027 [lamellipodium]
GO:0030032 [lamellipodium assembly]
GO:0030036 [actin cytoskeleton organization]
GO:0042384 [cilium assembly]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:1903955 [positive regulation of protein targeting to mitochondrion]
Show all
 683 aa
77.8 kDa 		No 0
ABLIM3-004
ENSP00000421183
ENST00000504238
O94929 [Direct mapping]
Actin-binding LIM protein 3
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001725 [stress fiber]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0030027 [lamellipodium]
GO:0030032 [lamellipodium assembly]
GO:0030036 [actin cytoskeleton organization]
GO:0042384 [cilium assembly]
GO:1903955 [positive regulation of protein targeting to mitochondrion]
Show all
 544 aa
61.6 kDa 		No 0
ABLIM3-005
ENSP00000420855
ENST00000508983
A0A0C4DGA7 [Direct mapping]
Actin-binding LIM protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0008270 [zinc ion binding]
GO:0030036 [actin cytoskeleton organization]
Show all
 650 aa
74.2 kDa 		No 0
ABLIM3-006
ENSP00000315841
ENST00000326685
O94929 [Direct mapping]
Actin-binding LIM protein 3
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001725 [stress fiber]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0030027 [lamellipodium]
GO:0030032 [lamellipodium assembly]
GO:0030036 [actin cytoskeleton organization]
GO:0042384 [cilium assembly]
GO:1903955 [positive regulation of protein targeting to mitochondrion]
Show all
 588 aa
67.1 kDa 		No 0
ABLIM3-011
ENSP00000430150
ENST00000517451
O94929 [Direct mapping]
Actin-binding LIM protein 3
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001725 [stress fiber]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007010 [cytoskeleton organization]
GO:0007411 [axon guidance]
GO:0008270 [zinc ion binding]
GO:0030027 [lamellipodium]
GO:0030032 [lamellipodium assembly]
GO:0030036 [actin cytoskeleton organization]
GO:0042384 [cilium assembly]
GO:1903955 [positive regulation of protein targeting to mitochondrion]
Show all
 169 aa
19.7 kDa 		No 0
ABLIM3-201
ENSP00000348938
ENST00000356541
A0A0A0MRD5 [Direct mapping]
Actin-binding LIM protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0007010 [cytoskeleton organization]
Show all
 170 aa
19.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.