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MUC13

GENERAL INFORMATION

Gene name

 MUC13

Gene description

 Mucin 13, cell surface associated

Protein class

 Predicted membrane proteins
Predicted secreted proteins

Predicted localization

 Membrane,Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (colon, duodenum, rectum, small intestine)
GTEx:Group enriched (colon, small intestine)
FANTOM5:Group enriched (colon, small intestine)

Protein evidence

 Evidence at protein level

Protein expression

 Selective cytoplasmic expression in gastrointestinal goblet cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA045163
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Duodenum

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (colon, duodenum, rectum, small intestine)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (colon, small intestine)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (colon, small intestine)

GENE INFORMATION

Gene name

 MUC13 (HGNC Symbol)

Synonyms

 DRCC1

Description

 Mucin 13, cell surface associated (HGNC Symbol)

Entrez gene summary

 Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008]

Chromosome

 3

Cytoband

 q21.2

Chromosome location (bp)

 124905442 - 124953819

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000173702 (version 83.38)

Entrez gene

 56667

UniProt

 Q9H3R2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H3R2

Antibodypedia

 MUC13 antibodies

PROTEIN BROWSER
MUC13-001
MUC13-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MUC13-001
ENSP00000485028
ENST00000616727
Q9H3R2 [Direct mapping]
Mucin-13
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005796 [Golgi lumen]
GO:0005829 [cytosol]
GO:0006493 [protein O-linked glycosylation]
GO:0016021 [integral component of membrane]
GO:0016266 [O-glycan processing]
GO:0016324 [apical plasma membrane]
GO:0030277 [maintenance of gastrointestinal epithelium]
GO:0042803 [protein homodimerization activity]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0070062 [extracellular exosome]
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 512 aa
54.6 kDa 		Yes 1
MUC13-003
ENSP00000418660
ENST00000478191
C9IZG1 [Direct mapping]
Mucin-13
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
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 184 aa
19.9 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.