Tissue expression of NDUFA11 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	NDUFA11
Gene description	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
Protein class	Disease related genes Plasma proteins Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Mixed
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	NDUFA11 (HGNC Symbol)
Synonyms	B14.7
Description	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa (HGNC Symbol)
Entrez gene summary	This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	5891276 - 5904006
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174886 (version 83.38)
Entrez gene	126328
UniProt	Q86Y39 (UniProt - Evidence at protein level)
neXtProt	NX_Q86Y39
Antibodypedia	NDUFA11 antibodies

PROTEIN BROWSER

NDUFA11-001	NDUFA11-002	NDUFA11-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NDUFA11-001 ENSP00000389160 ENST00000418389	Q86Y39 [Direct mapping] NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005747 [mitochondrial respiratory chain complex I] GO:0016021 [integral component of membrane] GO:0022904 [respiratory electron transport chain] GO:0044237 [cellular metabolic process] GO:0044281 [small molecule metabolic process] Show all	228 aa 23.4 kDa	No	0
NDUFA11-002 ENSP00000311740 ENST00000308961	Q86Y39 [Direct mapping] NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005747 [mitochondrial respiratory chain complex I] GO:0016021 [integral component of membrane] GO:0022904 [respiratory electron transport chain] GO:0044237 [cellular metabolic process] GO:0044281 [small molecule metabolic process] Show all	141 aa 14.9 kDa	No	3
NDUFA11-004 ENSP00000467706 ENST00000592634	K7EQ77 [Direct mapping] NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	120 aa 12.7 kDa	No	0