Tissue expression of FUT1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	FUT1
Gene description	Fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
Protein class	Blood group antigen proteins Enzymes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Mixed
FANTOM5:	Not detected

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	FUT1 (HGNC Symbol)
Synonyms	H, HSC
Description	Fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	q13.33
Chromosome location (bp)	48748011 - 48755390
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000174951 (version 83.38)
Entrez gene	2523
UniProt	P19526 (UniProt - Evidence at transcript level)
neXtProt	NX_P19526
Antibodypedia	FUT1 antibodies

PROTEIN BROWSER

FUT1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FUT1-001 ENSP00000312021 ENST00000310160	P19526 [Direct mapping] Galactoside 2-alpha-L-fucosyltransferase 1 Q6IZA2 [Target identity:100%; Query identity:100%] Alpha(1,2) fucosyltransferase 1; Alpha(1,2)fucosyltransferase; Fucosyltransferase; HCG16221 Show all	Enzymes ENZYME proteins Transferases Blood group antigen proteins Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005794 [Golgi apparatus] GO:0005887 [integral component of plasma membrane] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0008107 [galactoside 2-alpha-L-fucosyltransferase activity] GO:0008417 [fucosyltransferase activity] GO:0016020 [membrane] GO:0032580 [Golgi cisterna membrane] GO:0036065 [fucosylation] GO:0042355 [L-fucose catabolic process] Show all	365 aa 41.3 kDa	No	1