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Most cancer tissues showed moderate cytoplasmic immunoreactivity. Prostate and breast cancers along with several malignant carcinoids, colorectal and ovarian cancers were strongly stained. Several skin cancers were weakly stained or negative.
Cancer cells displayed moderate to strong granular cytoplasmic positivity. Several renal cancers displayed weak staining or were negative.
GENE INFORMATION
Gene name
KLC2 (HGNC Symbol)
Synonyms
FLJ12387
Description
Kinesin light chain 2 (HGNC Symbol)
Entrez gene summary
Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Kinesin consists of 2 light chains, such as KLC2, and 2 heavy chains (see KIF5B; MIM 602809) in a 1:1 stoichiometric ratio (Rahman et al., 1998 [PubMed 9624122]).[supplied by OMIM, Mar 2008]