Tissue expression of CATSPER1 - Summary

GENERAL INFORMATION
Gene name	CATSPER1
Gene description	Cation channel, sperm associated 1
Protein class	Disease related genes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	CATSPER1 (HGNC Symbol)
Synonyms	CATSPER
Description	Cation channel, sperm associated 1 (HGNC Symbol)
Entrez gene summary	Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q13.1
Chromosome location (bp)	66016752 - 66026517
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000175294 (version 83.38)
Entrez gene	117144
UniProt	Q8NEC5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NEC5
Antibodypedia	CATSPER1 antibodies

PROTEIN BROWSER

CATSPER1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CATSPER1-001 ENSP00000309052 ENST00000312106	Q8NEC5 [Direct mapping] Cation channel sperm-associated protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Disease related genes Show all	GO:0005216 [ion channel activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0006811 [ion transport] GO:0006816 [calcium ion transport] GO:0007275 [multicellular organismal development] GO:0007283 [spermatogenesis] GO:0007338 [single fertilization] GO:0007342 [fusion of sperm to egg plasma membrane] GO:0016020 [membrane] GO:0030154 [cell differentiation] GO:0030317 [sperm motility] GO:0031514 [motile cilium] GO:0032504 [multicellular organism reproduction] GO:0034220 [ion transmembrane transport] GO:0034765 [regulation of ion transmembrane transport] GO:0035036 [sperm-egg recognition] GO:0036128 [CatSper complex] GO:0051924 [regulation of calcium ion transport] GO:0055085 [transmembrane transport] GO:0060296 [regulation of cilium beat frequency involved in ciliary motility] GO:0070509 [calcium ion import] GO:0070588 [calcium ion transmembrane transport] GO:0086010 [membrane depolarization during action potential] Show all	780 aa 90.1 kDa	No	7