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Most cancer cells were negative. Cases of gliomas, endometrial, skin, liver, pancreatic and gastric cancers showed moderate cytoplasmic immunoreactivity.
GENE INFORMATION
Gene name
ASCL3 (HGNC Symbol)
Synonyms
bHLHa42, HASH3, Sgn1
Description
Achaete-scute family bHLH transcription factor 3 (HGNC Symbol)
Entrez gene summary
Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]