Cell atlas - DEFB103A - The Human Protein Atlas

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DEFB103A

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	DEFB103A
Gene description	Defensin, beta 103A
Protein class	Predicted secreted proteins Transporters
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	DEFB103A (HGNC Symbol)
Synonyms	DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3
Description	Defensin, beta 103A (HGNC Symbol)
Entrez gene summary	Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, an antibiotic peptide which is induced by bacteria and interferon gamma, and which displays antimicrobial activity against S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. [provided by RefSeq, Oct 2014]
Chromosome	8
Cytoband	p23.1
Chromosome location (bp)	7881204 - 7882664
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000176797 (version 83.38)
Entrez gene	414325
UniProt	P81534 (UniProt - Evidence at protein level)
neXtProt	NX_P81534
Antibodypedia	DEFB103A antibodies

PROTEIN BROWSER

DEFB103A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DEFB103A-001 ENSP00000320951 ENST00000314357	P81534 [Direct mapping] Beta-defensin 103 Show all	Transporters Transporter channels and pores MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] GO:0005796 [Golgi lumen] GO:0006952 [defense response] GO:0006965 [positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria] GO:0042742 [defense response to bacterium] GO:0045087 [innate immune response] Show all	67 aa 7.7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.