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DEFB103A

GENERAL INFORMATION

Gene name

 DEFB103A

Gene description

 Defensin, beta 103A

Protein class

 Predicted secreted proteins
Transporters

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Tissue enhanced (tonsil)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 DEFB103A (HGNC Symbol)

Synonyms

 DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3

Description

 Defensin, beta 103A (HGNC Symbol)

Entrez gene summary

 Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, an antibiotic peptide which is induced by bacteria and interferon gamma, and which displays antimicrobial activity against S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. [provided by RefSeq, Oct 2014]

Chromosome

 8

Cytoband

 p23.1

Chromosome location (bp)

 7881204 - 7882664

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000176797 (version 83.38)

Entrez gene

 414325

UniProt

 P81534 (UniProt - Evidence at protein level)

neXtProt

 NX_P81534

Antibodypedia

 DEFB103A antibodies

PROTEIN BROWSER
DEFB103A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DEFB103A-001
ENSP00000320951
ENST00000314357
P81534 [Direct mapping]
Beta-defensin 103
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Transporters
   Transporter channels and pores
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
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GO:0005576 [extracellular region]
GO:0005796 [Golgi lumen]
GO:0006952 [defense response]
GO:0006965 [positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria]
GO:0042742 [defense response to bacterium]
GO:0045087 [innate immune response]
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 67 aa
7.7 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.