Tissue expression of CRACR2B - Summary - The Human Protein Atlas

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CRACR2B

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CRACR2B
Gene description	Calcium release activated channel regulator 2B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (salivary gland)
GTEx:	Expressed in all
FANTOM5:	Group enriched (pancreas, salivary gland)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Pending external verification. Caution, Splice and/or transcript discrepancy exists.
Reliability score	Approved based on 1 antibody. HPA046217
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (salivary gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (pancreas, salivary gland)

GENE INFORMATION
Gene name	CRACR2B (HGNC Symbol)
Synonyms	EFCAB4A, MGC45840
Description	Calcium release activated channel regulator 2B (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p15.5
Chromosome location (bp)	826144 - 831991
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177685 (version 83.38)
Entrez gene	283229
UniProt	Q8N4Y2 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N4Y2
Antibodypedia	CRACR2B antibodies

PROTEIN BROWSER

CRACR2B-001	CRACR2B-007	CRACR2B-009	CRACR2B-010	CRACR2B-011	CRACR2B-012	CRACR2B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CRACR2B-001 ENSP00000432334 ENST00000528542	Q8N4Y2 [Direct mapping] EF-hand calcium-binding domain-containing protein 4A Show all	Predicted intracellular proteins Show all	GO:0002115 [store-operated calcium entry] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	294 aa 32.7 kDa	No	0
CRACR2B-007 ENSP00000435299 ENST00000525077	Q8N4Y2 [Direct mapping] EF-hand calcium-binding domain-containing protein 4A Show all	Predicted intracellular proteins Show all	GO:0002115 [store-operated calcium entry] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:2001256 [regulation of store-operated calcium entry] Show all	399 aa 45 kDa	No	0
CRACR2B-009 ENSP00000436624 ENST00000530183	E9PHZ8 [Direct mapping] EF-hand calcium-binding domain-containing protein 4A Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] Show all	53 aa 5.6 kDa	No	0
CRACR2B-010 ENSP00000433602 ENST00000533803	E9PK04 [Direct mapping] EF-hand calcium-binding domain-containing protein 4A Show all	Predicted intracellular proteins Show all		81 aa 8.6 kDa	No	0
CRACR2B-011 ENSP00000432726 ENST00000527089	E9PPF3 [Direct mapping] EF-hand calcium-binding domain-containing protein 4A Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] Show all	88 aa 9.5 kDa	No	0
CRACR2B-012 ENSP00000434198 ENST00000528315	E9PRE5 [Direct mapping] EF-hand calcium-binding domain-containing protein 4A Show all	Predicted intracellular proteins Show all		34 aa 3.4 kDa	No	0
CRACR2B-201 ENSP00000409256 ENST00000450448	Q8N4Y2 [Direct mapping] EF-hand calcium-binding domain-containing protein 4A Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0002115 [store-operated calcium entry] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	294 aa 32.7 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.