Expression of TMEM107 in cancer - Summary - The Human Protein Atlas

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TMEM107

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM107
Gene description	Transmembrane protein 107
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Approved based on 1 antibody. HPA052555
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable).
Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA052555

GENE INFORMATION
Gene name	TMEM107 (HGNC Symbol)
Synonyms	MGC10744
Description	Transmembrane protein 107 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.1
Chromosome location (bp)	8173237 - 8176399
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000179029 (version 83.38)
Entrez gene	84314
UniProt	Q6UX40 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6UX40
Antibodypedia	TMEM107 antibodies

PROTEIN BROWSER

TMEM107-001	TMEM107-002	TMEM107-003	TMEM107-004	TMEM107-005	TMEM107-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM107-001 ENSP00000436674 ENST00000533070	Q6UX40 [Direct mapping] Transmembrane protein 107 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0042384 [cilium assembly] Show all	139 aa 15.2 kDa	No	3
TMEM107-002 ENSP00000402732 ENST00000437139	Q6UX40 [Direct mapping] Transmembrane protein 107 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0042384 [cilium assembly] Show all	140 aa 15.5 kDa	No	4
TMEM107-003 ENSP00000314116 ENST00000316425	Q6UX40 [Direct mapping] Transmembrane protein 107 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0021532 [neural tube patterning] GO:0042384 [cilium assembly] GO:0042733 [embryonic digit morphogenesis] Show all	146 aa 16.2 kDa	No	3
TMEM107-004 ENSP00000404753 ENST00000449985	B2RDT5 [Direct mapping] Transmembrane protein 107; cDNA, FLJ96758 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	35 aa 3.9 kDa	No	1
TMEM107-005 ENSP00000433148 ENST00000532998	B3KNL7 [Direct mapping] Transmembrane protein 107; cDNA FLJ14907 fis, clone PLACE1005934 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	107 aa 11.5 kDa	No	2
TMEM107-010 ENSP00000389420 ENST00000431792	E9PIH0 [Direct mapping] Transmembrane protein 107 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	74 aa 8.3 kDa	No	2

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.