Cell atlas - ARID3B - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ARID3B

TISSUE

premium

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	ARID3B
Gene description	AT rich interactive domain 3B (BRIGHT-like)
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Cell line enhanced (NTERA-2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA050320
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (NTERA-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA050320	A-431	Nucleoplasm
	HPA050320	CACO-2	Nucleoplasm
	HPA050320	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	ARID3B (HGNC Symbol)
Synonyms	BDP, DRIL2
Description	AT rich interactive domain 3B (BRIGHT-like) (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
Chromosome	15
Cytoband	q24.1
Chromosome location (bp)	74541177 - 74598131
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000179361 (version 83.38)
Entrez gene	10620
UniProt	Q8IVW6 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IVW6
Antibodypedia	ARID3B antibodies

PROTEIN BROWSER

ARID3B-001	ARID3B-004	ARID3B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARID3B-001 ENSP00000343126 ENST00000346246	Q8IVW6 [Direct mapping] AT-rich interactive domain-containing protein 3B Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0008150 [biological_process] Show all	560 aa 60.6 kDa	No	0
ARID3B-004 ENSP00000455668 ENST00000566147	H3BQ92 [Direct mapping] AT-rich interactive domain-containing protein 3B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	138 aa 14.9 kDa	No	0
ARID3B-201 ENSP00000477878 ENST00000622429	Q8IVW6 [Direct mapping] AT-rich interactive domain-containing protein 3B Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0001205 [transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006366 [transcription from RNA polymerase II promoter] GO:0008150 [biological_process] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	561 aa 60.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.