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GIPC3

GENERAL INFORMATION

Gene name

 GIPC3

Gene description

 GIPC PDZ domain containing family, member 3

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Tissue enhanced (vagina)

Protein evidence

 Evidence at protein level

Protein expression

 Membranous expression in most tissues with additional cytoplasmic expression in some tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA061258
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (vagina)

GENE INFORMATION

Gene name

 GIPC3 (HGNC Symbol)

Synonyms

 C19orf64, DFNB15, DFNB72, DFNB95

Description

 GIPC PDZ domain containing family, member 3 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene belongs to the GIPC family. Studies in mice suggest that this gene is required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion in the ear. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2011]

Chromosome

 19

Cytoband

 p13.3

Chromosome location (bp)

 3585553 - 3593541

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000179855 (version 83.38)

Entrez gene

 126326

UniProt

 Q8TF64 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TF64

Antibodypedia

 GIPC3 antibodies

PROTEIN BROWSER
GIPC3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GIPC3-001
ENSP00000319254
ENST00000322315
Q8TF64 [Direct mapping]
PDZ domain-containing protein GIPC3
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Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
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 312 aa
34 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.