Cell atlas - TSHZ1 - The Human Protein Atlas

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TSHZ1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	TSHZ1
Gene description	Teashirt zinc finger homeobox 1
Protein class	Disease related genes Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Cell line enhanced (HDLM-2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA006982
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HDLM-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA006982	A-431	Nucleoplasm
	HPA006982	U-2 OS	Nucleoplasm
	HPA006982	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	TSHZ1 (HGNC Symbol)
Synonyms	NY-CO-33, SDCCAG33, TSH1
Description	Teashirt zinc finger homeobox 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome. [provided by RefSeq, Jan 2012]
Chromosome	18
Cytoband	q22.3
Chromosome location (bp)	75210755 - 75289950
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000179981 (version 83.38)
Entrez gene	10194
UniProt	Q6ZSZ6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6ZSZ6
Antibodypedia	TSHZ1 antibodies

PROTEIN BROWSER

TSHZ1-001	TSHZ1-002	TSHZ1-003	TSHZ1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TSHZ1-001 ENSP00000323584 ENST00000322038	Q6ZSZ6 [Direct mapping] Teashirt homolog 1 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	1032 aa 112.7 kDa	No	0
TSHZ1-002 ENSP00000453834 ENST00000560918	H0YN23 [Direct mapping] Teashirt homolog 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0010468 [regulation of gene expression] GO:0046872 [metal ion binding] Show all	277 aa 30.3 kDa	No	0
TSHZ1-003 ENSP00000452718 ENST00000560661	H0YKA1 [Direct mapping] Teashirt homolog 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0010468 [regulation of gene expression] Show all	78 aa 8.5 kDa	No	0
TSHZ1-005 ENSP00000464391 ENST00000580243	Q6ZSZ6 [Direct mapping] Teashirt homolog 1 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0009952 [anterior/posterior pattern specification] GO:0042474 [middle ear morphogenesis] GO:0046872 [metal ion binding] GO:0060023 [soft palate development] Show all	1077 aa 117.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.