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MYLPF

GENERAL INFORMATION

Gene name

 MYLPF

Gene description

 Myosin light chain, phosphorylatable, fast skeletal muscle

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (skeletal muscle)
GTEx:Tissue enriched (skeletal muscle)
FANTOM5:Tissue enriched (skeletal muscle)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in skeletal muscle.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Approved based on 1 antibody.
HPA039262
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)

GENE INFORMATION

Gene name

 MYLPF (HGNC Symbol)

Synonyms

 HUMMLC2B, MRLC2, MYL11

Description

 Myosin light chain, phosphorylatable, fast skeletal muscle (HGNC Symbol)

Entrez gene summary

Chromosome

 16

Cytoband

 p11.2

Chromosome location (bp)

 30370934 - 30377991

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000180209 (version 83.38)

Entrez gene

 29895

UniProt

 Q96A32 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q96A32

Antibodypedia

 MYLPF antibodies

PROTEIN BROWSER
MYLPF-001
MYLPF-002
MYLPF-003
MYLPF-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MYLPF-001
ENSP00000325239
ENST00000322861
Q96A32 [Direct mapping]
Myosin regulatory light chain 2, skeletal muscle isoform
A0A024QZG6 [Target identity:100%; Query identity:100%]
Fast skeletal myosin light chain 2, isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005509 [calcium ion binding]
GO:0005765 [lysosomal membrane]
GO:0005829 [cytosol]
GO:0005859 [muscle myosin complex]
GO:0006936 [muscle contraction]
GO:0006955 [immune response]
GO:0007519 [skeletal muscle tissue development]
GO:0008307 [structural constituent of muscle]
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 169 aa
19 kDa 		No 0
MYLPF-002
ENSP00000454444
ENST00000563718
H3BML9 [Direct mapping]
Myosin regulatory light chain 2, skeletal muscle isoform
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005509 [calcium ion binding]
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 118 aa
13.2 kDa 		No 0
MYLPF-003
ENSP00000455356
ENST00000566955
H3BPK4 [Direct mapping]
Myosin regulatory light chain 2, skeletal muscle isoform
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   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005509 [calcium ion binding]
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 199 aa
22 kDa 		No 0
MYLPF-005
ENSP00000454694
ENST00000568749
H3BN54 [Direct mapping]
Myosin regulatory light chain 2, skeletal muscle isoform
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
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 135 aa
15.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.