Moderate to strong nuclear and cytoplasmic positivity was observed in a majority of cancer tissues. Lymphomas, testicular, urothelial and several lung cancers were negative.
ALX1 (HGNC Symbol)
ALX homeobox 1 (HGNC Symbol)
Entrez gene summary
The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly. [provided by RefSeq, Jul 2008]