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ARSJ

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GENERAL INFORMATION

Gene name

 ARSJ

Gene description

 Arylsulfatase family, member J

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the actin filaments. In addition localized to the nucleoli.

RNA cell category

 Cell line enhanced (TIME)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Actin filaments (supported)

Additional location

 In addition localized to the Nucleoli (approved)

Single-cell variation

 Single-cell variation in protein expression observed.

DATA RELIABILITY

Reliability score

 Supported based on 2 antibodies.
HPA036481 , HPA036482
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (TIME)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the actin filaments. In addition localized to the nucleoli.

Main location

 Actin filaments (supported)

Additional location

 Nucleoli (approved)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA036481 BJ Actin filaments Spatial
HPA036481 U-2 OS No staining    
HPA036481 U-251 MG Nucleoli
HPA036482 BJ Actin filaments Spatial
HPA036482 U-2 OS No staining    
HPA036482 U-251 MG No staining    

GENE INFORMATION

Gene name

 ARSJ (HGNC Symbol)

Synonyms

 FLJ23548

Description

 Arylsulfatase family, member J (HGNC Symbol)

Entrez gene summary

 Sulfatases (EC 3.1.5.6), such as ARSJ, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008]

Chromosome

 4

Cytoband

 q26

Chromosome location (bp)

 113900284 - 113979727

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000180801 (version 83.38)

Entrez gene

 79642

UniProt

 Q5FYB0 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q5FYB0

Antibodypedia

 ARSJ antibodies

PROTEIN BROWSER
ARSJ-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARSJ-001
ENSP00000320219
ENST00000315366
Q5FYB0 [Direct mapping]
Arylsulfatase J
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004065 [arylsulfatase activity]
GO:0005576 [extracellular region]
GO:0005788 [endoplasmic reticulum lumen]
GO:0006665 [sphingolipid metabolic process]
GO:0006687 [glycosphingolipid metabolic process]
GO:0008152 [metabolic process]
GO:0008484 [sulfuric ester hydrolase activity]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
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 599 aa
67.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.