Cell atlas - ACBD3 - The Human Protein Atlas

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ACBD3

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus

Human cell
	Golgi Apparatus

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GENERAL INFORMATION
Gene name	ACBD3
Gene description	Acyl-CoA binding domain containing 3
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the Golgi apparatus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA015594
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the Golgi apparatus.

Main location

Golgi apparatus (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA015594	A-431	Golgi apparatus
	HPA015594	U-2 OS	Golgi apparatus
	HPA015594	U-251 MG	Golgi apparatus

GENE INFORMATION
Gene name	ACBD3 (HGNC Symbol)
Synonyms	GCP60, GOCAP1, GOLPH1, PAP7
Description	Acyl-CoA binding domain containing 3 (HGNC Symbol)
Entrez gene summary	The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q42.12
Chromosome location (bp)	226144679 - 226186730
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000182827 (version 83.38)
Entrez gene	64746
UniProt	Q9H3P7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H3P7
Antibodypedia	ACBD3 antibodies

PROTEIN BROWSER

ACBD3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACBD3-001 ENSP00000355777 ENST00000366812	Q9H3P7 [Direct mapping] Golgi resident protein GCP60 A0A024R3P9 [Target identity:100%; Query identity:100%] Acyl-Coenzyme A binding domain containing 3, isoform CRA_a Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005794 [Golgi apparatus] GO:0006694 [steroid biosynthetic process] GO:0006810 [transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034237 [protein kinase A regulatory subunit binding] Show all	528 aa 60.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.