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ACBD3

GENERAL INFORMATION

Gene name

 ACBD3

Gene description

 Acyl-CoA binding domain containing 3

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Granular expression in several tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Uncertain based on 1 antibody.
HPA015594
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA015594

GENE INFORMATION

Gene name

 ACBD3 (HGNC Symbol)

Synonyms

 GCP60, GOCAP1, GOLPH1, PAP7

Description

 Acyl-CoA binding domain containing 3 (HGNC Symbol)

Entrez gene summary

 The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation. [provided by RefSeq, Jul 2008]

Chromosome

 1

Cytoband

 q42.12

Chromosome location (bp)

 226144679 - 226186730

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000182827 (version 83.38)

Entrez gene

 64746

UniProt

 Q9H3P7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H3P7

Antibodypedia

 ACBD3 antibodies

PROTEIN BROWSER
ACBD3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ACBD3-001
ENSP00000355777
ENST00000366812
Q9H3P7 [Direct mapping]
Golgi resident protein GCP60
A0A024R3P9 [Target identity:100%; Query identity:100%]
Acyl-Coenzyme A binding domain containing 3, isoform CRA_a
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000062 [fatty-acyl-CoA binding]
GO:0000139 [Golgi membrane]
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005794 [Golgi apparatus]
GO:0006694 [steroid biosynthetic process]
GO:0006810 [transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0034237 [protein kinase A regulatory subunit binding]
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 528 aa
60.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.