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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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FAM19A1
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

FAM19A1

Gene description

Family with sequence similarity 19 (chemokine (C-C motif)-like), member A1

Protein class

Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (cerebral cortex)
GTEx:Group enriched (cerebral cortex, hippocampus, hypothalamus)
FANTOM5:Group enriched (brain, hippocampus)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several tissues, distinct expression in the brain.

DATA RELIABILITY

Data reliability
description

Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Reliability score

Approved based on 1 antibody.
HPA013407
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (cerebral cortex, hippocampus, hypothalamus)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (brain, hippocampus)

GENE INFORMATION

Gene name

FAM19A1 (HGNC Symbol)

Synonyms

TAFA-1

Description

Family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

p14.1

Chromosome location (bp)

68004216 - 68545625

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183662 (version 83.38)

Entrez gene

407738

UniProt

Q7Z5A9 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z5A9

Antibodypedia

FAM19A1 antibodies

PROTEIN BROWSER

FAM19A1-001
FAM19A1-002
FAM19A1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAM19A1-001
ENSP00000418575
ENST00000478136
Q7Z5A9 [Direct mapping]
Protein FAM19A1
Show all
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005783 [endoplasmic reticulum]
Show all
133 aa
14.9 kDa
Yes 0
FAM19A1-002
ENSP00000417496
ENST00000496687
Q7Z5A9 [Direct mapping]
Protein FAM19A1
Show all
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005783 [endoplasmic reticulum]
Show all
133 aa
14.9 kDa
Yes 0
FAM19A1-201
ENSP00000485030
ENST00000617084
A0A087X2J7 [Direct mapping]
Protein FAM19A1
Show all
Predicted intracellular proteins
Show all
52 aa
5.5 kDa
No 0

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The Human Protein Atlas project is funded
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