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CNGA2

GENERAL INFORMATION

Gene name

 CNGA2

Gene description

 Cyclic nucleotide gated channel alpha 2

Protein class

 Predicted membrane proteins
Voltage-gated ion channels

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Not detected
GTEx:Not detected

Protein evidence

 Evidence at protein level

Protein expression

 Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification. Antibody staining not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA015065
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected

GENE INFORMATION

Gene name

 CNGA2 (HGNC Symbol)

Synonyms

 CNCA, CNCA1, CNG2, FLJ46312, OCNC1, OCNCa, OCNCALPHA

Description

 Cyclic nucleotide gated channel alpha 2 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. [provided by RefSeq, Jan 2010]

Chromosome

 X

Cytoband

 q28

Chromosome location (bp)

 151738451 - 151745304

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000183862 (version 83.38)

Entrez gene

 1260

UniProt

 Q16280 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q16280

Antibodypedia

 CNGA2 antibodies

PROTEIN BROWSER
CNGA2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CNGA2-001
ENSP00000328478
ENST00000329903
Q16280 [Direct mapping]
Cyclic nucleotide-gated olfactory channel
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Voltage-gated ion channels
   Cyclic Nucleotide-Regulated Channels
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005216 [ion channel activity]
GO:0005222 [intracellular cAMP activated cation channel activity]
GO:0005223 [intracellular cGMP activated cation channel activity]
GO:0005249 [voltage-gated potassium channel activity]
GO:0005516 [calmodulin binding]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006996 [organelle organization]
GO:0007608 [sensory perception of smell]
GO:0016020 [membrane]
GO:0030552 [cAMP binding]
GO:0030553 [cGMP binding]
GO:0030660 [Golgi-associated vesicle membrane]
GO:0042391 [regulation of membrane potential]
GO:0050896 [response to stimulus]
GO:0055085 [transmembrane transport]
GO:0060170 [ciliary membrane]
GO:0071805 [potassium ion transmembrane transport]
Show all
 664 aa
76 kDa 		No 5

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.