Tissue expression of GAST - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

GAST

premium

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	GAST
Gene description	Gastrin
Protein class	Cancer-related genes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (stomach)
GTEx:	Tissue enriched (stomach)
FANTOM5:	Tissue enhanced (endometrium, placenta)

Protein evidence

Evidence at protein level

Protein expression

Selective cytoplasmic expression in a subset of cells in stomach

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. CAB000038
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (stomach)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (stomach)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (endometrium, placenta)

GENE INFORMATION
Gene name	GAST (HGNC Symbol)
Synonyms	GAS
Description	Gastrin (HGNC Symbol)
Entrez gene summary	Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q21.2
Chromosome location (bp)	41712326 - 41715969
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184502 (version 83.38)
Entrez gene	2520
UniProt	P01350 (UniProt - Evidence at protein level)
neXtProt	NX_P01350
Antibodypedia	GAST antibodies

PROTEIN BROWSER

GAST-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GAST-001 ENSP00000331358 ENST00000329402	P01350 [Direct mapping] Gastrin Gastrin-71 Gastrin-52 Big gastrin Gastrin Gastrin-14 Gastrin-6 A0A0E3VY36 [Target identity:100%; Query identity:100%] Gastrin Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Cancer-related genes Candidate cancer biomarkers Show all	GO:0005179 [hormone activity] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0032094 [response to food] Show all	101 aa 11.4 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.