Cell atlas - CA13 - The Human Protein Atlas

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CA13

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli
	Nucleus
	Vesicles

Human cell
	Nucleoli
	Nucleoplasm
	Vesicles

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GENERAL INFORMATION
Gene name	CA13
Gene description	Carbonic anhydrase XIII
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli. In addition localized to the nucleus & vesicles.
RNA cell category	Cell line enhanced (HEL)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (uncertain)
Additional location	In addition localized to the Nucleus (uncertain), Vesicles (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA024689
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HEL) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli. In addition localized to the nucleus & vesicles.

Main location

Nucleoli (uncertain)

Additional location

Nucleus (uncertain), Vesicles (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA024689	A-431	Nucleus
			Nucleoli
			Vesicles
	HPA024689	U-2 OS	Nucleoli
	HPA024689	U-251 MG	Nucleus
			Nucleoli
			Vesicles

GENE INFORMATION
Gene name	CA13 (HGNC Symbol)
Synonyms	CAXIII, FLJ37995, MGC59868
Description	Carbonic anhydrase XIII (HGNC Symbol)
Entrez gene summary	Carbonic anhydrases (CAs) are a family of zinc metalloenzymes. For background information on the CA family, see MIM 114800.[supplied by OMIM, Mar 2008]
Chromosome	8
Cytoband	q21.2
Chromosome location (bp)	85220587 - 85284073
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000185015 (version 83.38)
Entrez gene	377677
UniProt	Q8N1Q1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N1Q1
Antibodypedia	CA13 antibodies

PROTEIN BROWSER

CA13-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CA13-001 ENSP00000318912 ENST00000321764	Q8N1Q1 [Direct mapping] Carbonic anhydrase 13 Show all	Enzymes ENZYME proteins Lyases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004089 [carbonate dehydratase activity] GO:0005829 [cytosol] GO:0006730 [one-carbon metabolic process] GO:0008270 [zinc ion binding] GO:0015701 [bicarbonate transport] GO:0043209 [myelin sheath] GO:0043231 [intracellular membrane-bounded organelle] GO:0044281 [small molecule metabolic process] Show all	262 aa 29.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.