Cell atlas - RPS27L - The Human Protein Atlas

GENERAL INFORMATION
Gene name	RPS27L
Gene description	Ribosomal protein S27-like
Protein class	Predicted intracellular proteins Predicted secreted proteins Ribosomal proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol & endoplasmic reticulum. In addition localized to the nucleoli. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Endoplasmic reticulum (supported), Cytosol (supported)
Additional location	In addition localized to the Nucleoli (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA066851
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol & endoplasmic reticulum. In addition localized to the nucleoli. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Endoplasmic reticulum (supported), Cytosol (supported)

Additional location

Nucleoli (supported)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA066851	Hep G2	Endoplasmic reticulum
HPA066851	Hep G2	Cytosol
HPA066851	SK-MEL-30	Endoplasmic reticulum
HPA066851	SK-MEL-30	Cytosol
HPA066851	U-2 OS	Nucleoli
		Endoplasmic reticulum
		Cytosol

GENE INFORMATION
Gene name	RPS27L
Synonyms
Description	Ribosomal protein S27-like (HGNC Symbol)
Entrez gene summary	This gene encodes a protein sharing 96% amino acid similarity with ribosomal protein S27, which suggests the encoded protein may be a component of the 40S ribosomal subunit. [provided by RefSeq, Jul 2008]
Chromosome	15
Cytoband	q22.2
Chromosome location (bp)	63125872 - 63158021
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000185088 (version 83.38)
Entrez gene	51065
UniProt	Q71UM5 (UniProt - Evidence at protein level)
neXtProt	NX_Q71UM5
Antibodypedia	RPS27L antibodies

PROTEIN BROWSER

RPS27L-001	RPS27L-003	RPS27L-004	RPS27L-005	RPS27L-006	RPS27L-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPS27L-001 ENSP00000331019 ENST00000330964	Q71UM5 [Direct mapping] 40S ribosomal protein S27-like Show all	Ribosomal proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000028 [ribosomal small subunit assembly] GO:0003735 [structural constituent of ribosome] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005840 [ribosome] GO:0006281 [DNA repair] GO:0006412 [translation] GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0006974 [cellular response to DNA damage stimulus] GO:0008494 [translation activator activity] GO:0008656 [cysteine-type endopeptidase activator activity involved in apoptotic process] GO:0022627 [cytosolic small ribosomal subunit] GO:0031571 [mitotic G1 DNA damage checkpoint] GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] GO:0044822 [poly(A) RNA binding] GO:0045727 [positive regulation of translation] GO:0046872 [metal ion binding] Show all	84 aa 9.5 kDa	No	0
RPS27L-003 ENSP00000412026 ENST00000455271	C9J1C5 [Direct mapping] 40S ribosomal protein S27 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] GO:0046872 [metal ion binding] Show all	52 aa 5.6 kDa	No	0
RPS27L-004 ENSP00000405300 ENST00000411926	C9J1C5 [Direct mapping] 40S ribosomal protein S27 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] GO:0046872 [metal ion binding] Show all	52 aa 5.6 kDa	No	0
RPS27L-005 ENSP00000402423 ENST00000439025	C9JLI6 [Direct mapping] 40S ribosomal protein S27 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] GO:0046872 [metal ion binding] Show all	97 aa 10.9 kDa	No	0
RPS27L-006 ENSP00000453764 ENST00000462430	H0YMV8 [Direct mapping] 40S ribosomal protein S27 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] GO:0046872 [metal ion binding] Show all	100 aa 11.3 kDa	Yes	0
RPS27L-008 ENSP00000489261 ENST00000635699		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] Show all	52 aa 5.6 kDa	No	0