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RPS27L

GENERAL INFORMATION

Gene name

 RPS27L

Gene description

 Ribosomal protein S27-like

Protein class

 Predicted intracellular proteins
Predicted secreted proteins
Ribosomal proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable).
Endometrial cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 RPS27L

Synonyms

Description

 Ribosomal protein S27-like (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein sharing 96% amino acid similarity with ribosomal protein S27, which suggests the encoded protein may be a component of the 40S ribosomal subunit. [provided by RefSeq, Jul 2008]

Chromosome

 15

Cytoband

 q22.2

Chromosome location (bp)

 63125872 - 63158021

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000185088 (version 83.38)

Entrez gene

 51065

UniProt

 Q71UM5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q71UM5

Antibodypedia

 RPS27L antibodies

PROTEIN BROWSER
RPS27L-001
RPS27L-003
RPS27L-004
RPS27L-005
RPS27L-006
RPS27L-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPS27L-001
ENSP00000331019
ENST00000330964
Q71UM5 [Direct mapping]
40S ribosomal protein S27-like
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Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000028 [ribosomal small subunit assembly]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005840 [ribosome]
GO:0006281 [DNA repair]
GO:0006412 [translation]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0008494 [translation activator activity]
GO:0008656 [cysteine-type endopeptidase activator activity involved in apoptotic process]
GO:0022627 [cytosolic small ribosomal subunit]
GO:0031571 [mitotic G1 DNA damage checkpoint]
GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator]
GO:0044822 [poly(A) RNA binding]
GO:0045727 [positive regulation of translation]
GO:0046872 [metal ion binding]
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 84 aa
9.5 kDa 		No 0
RPS27L-003
ENSP00000412026
ENST00000455271
C9J1C5 [Direct mapping]
40S ribosomal protein S27
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0046872 [metal ion binding]
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 52 aa
5.6 kDa 		No 0
RPS27L-004
ENSP00000405300
ENST00000411926
C9J1C5 [Direct mapping]
40S ribosomal protein S27
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0046872 [metal ion binding]
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 52 aa
5.6 kDa 		No 0
RPS27L-005
ENSP00000402423
ENST00000439025
C9JLI6 [Direct mapping]
40S ribosomal protein S27
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0046872 [metal ion binding]
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 97 aa
10.9 kDa 		No 0
RPS27L-006
ENSP00000453764
ENST00000462430
H0YMV8 [Direct mapping]
40S ribosomal protein S27
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0046872 [metal ion binding]
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 100 aa
11.3 kDa 		Yes 0
RPS27L-008
ENSP00000489261
ENST00000635699
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
 52 aa
5.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.