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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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TNFAIP2
  • premium

    TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

TNFAIP2

Gene description

Tumor necrosis factor, alpha-induced protein 2

Protein class

Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Transporters

Predicted localization

Intracellular

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic and nuclear expression in several tissues, most abundant in immune cells and urinary bladder.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 1 antibody.
CAB004598
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Urinary bladder

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

TNFAIP2 (HGNC Symbol)

Synonyms

B94, EXOC3L3

Description

Tumor necrosis factor, alpha-induced protein 2 (HGNC Symbol)

Entrez gene summary

This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q32.32

Chromosome location (bp)

103123442 - 103137439

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000185215 (version 83.38)

Entrez gene

7127

UniProt

Q03169 (UniProt - Evidence at transcript level)

neXtProt

NX_Q03169

Antibodypedia

TNFAIP2 antibodies

PROTEIN BROWSER

TNFAIP2-001
TNFAIP2-004
TNFAIP2-005
TNFAIP2-006
TNFAIP2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TNFAIP2-001
ENSP00000452634
ENST00000560869
Q03169 [Direct mapping]
Tumor necrosis factor alpha-induced protein 2
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0000149 [SNARE binding]
GO:0001525 [angiogenesis]
GO:0005615 [extracellular space]
GO:0006887 [exocytosis]
GO:0030154 [cell differentiation]
GO:0051601 [exocyst localization]
Show all
654 aa
72.7 kDa
No 0
TNFAIP2-004
ENSP00000453142
ENST00000560670
H0YLC0 [Direct mapping]
Tumor necrosis factor alpha-induced protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0000149 [SNARE binding]
GO:0006887 [exocytosis]
GO:0051601 [exocyst localization]
Show all
347 aa
39.1 kDa
No 0
TNFAIP2-005
ENSP00000452914
ENST00000559255
H0YKR7 [Direct mapping]
Tumor necrosis factor alpha-induced protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0000149 [SNARE binding]
GO:0006887 [exocytosis]
GO:0051601 [exocyst localization]
Show all
243 aa
27.2 kDa
No 0
TNFAIP2-006
ENSP00000453103
ENST00000558056
H0YL88 [Direct mapping]
Tumor necrosis factor alpha-induced protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0000149 [SNARE binding]
GO:0006887 [exocytosis]
GO:0051601 [exocyst localization]
Show all
39 aa
4.3 kDa
No 0
TNFAIP2-201
ENSP00000332326
ENST00000333007
Q03169 [Direct mapping]
Tumor necrosis factor alpha-induced protein 2
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0000149 [SNARE binding]
GO:0001525 [angiogenesis]
GO:0005615 [extracellular space]
GO:0006887 [exocytosis]
GO:0030154 [cell differentiation]
GO:0051601 [exocyst localization]
Show all
654 aa
72.7 kDa
No 0

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