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Cancer cells generally displayed weak to moderate positivity. Most lymphomas were negative.
GENE INFORMATION
Gene name
PRMT3 (HGNC Symbol)
Synonyms
HRMT1L3
Description
Protein arginine methyltransferase 3 (HGNC Symbol)
Entrez gene summary
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
A0A0A0MSN7 [Direct mapping] Protein arginine N-methyltransferase 3
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SPOCTOPUS predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)