Cell atlas - ATP4B - The Human Protein Atlas

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ATP4B

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ATP4B
Gene description	ATPase, H+/K+ exchanging, beta polypeptide
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ATP4B (HGNC Symbol)
Synonyms	ATP6B
Description	ATPase, H+/K+ exchanging, beta polypeptide (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]
Chromosome	13
Cytoband	q34
Chromosome location (bp)	113648804 - 113658186
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000186009 (version 83.38)
Entrez gene	496
UniProt	P51164 (UniProt - Evidence at protein level)
neXtProt	NX_P51164
Antibodypedia	ATP4B antibodies

PROTEIN BROWSER

ATP4B-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATP4B-001 ENSP00000334216 ENST00000335288	P51164 [Direct mapping] Potassium-transporting ATPase subunit beta Show all	Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005890 [sodium:potassium-exchanging ATPase complex] GO:0006813 [potassium ion transport] GO:0006814 [sodium ion transport] GO:0007155 [cell adhesion] GO:0008900 [hydrogen:potassium-exchanging ATPase activity] GO:0010243 [response to organonitrogen compound] GO:0032496 [response to lipopolysaccharide] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:1902600 [hydrogen ion transmembrane transport] Show all	291 aa 33.4 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.