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Gene name

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Chromosome

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Reliability

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Method

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Cancer

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BTN3A2
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

BTN3A2

Gene description

Butyrophilin, subfamily 3, member A2

Protein class

Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Intracellular,Membrane,Secreted

Number of transcripts

10
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Mixed

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

Uncertain based on 1 antibody.
CAB019392
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

BTN3A2 (HGNC Symbol)

Synonyms

BTN3.2

Description

Butyrophilin, subfamily 3, member A2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the immunoglobulin superfamily, which resides in the juxta-telomeric region of the major histocompatability class 1 locus and is clustered with the other family members on chromosome 6. The encoded protein may be involved in the adaptive immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]

Chromosome

6

Cytoband

p22.2

Chromosome location (bp)

26365159 - 26378320

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186470 (version 83.38)

Entrez gene

11118

UniProt

P78410 (UniProt - Evidence at protein level)

neXtProt

NX_P78410

Antibodypedia

BTN3A2 antibodies

PROTEIN BROWSER

BTN3A2-001
BTN3A2-002
BTN3A2-003
BTN3A2-004
BTN3A2-005
BTN3A2-006
BTN3A2-008
BTN3A2-016
BTN3A2-201
BTN3A2-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BTN3A2-001
ENSP00000348751
ENST00000356386
P78410 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002456 [T cell mediated immunity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0072643 [interferon-gamma secretion]
Show all
334 aa
36.4 kDa
Yes 1
BTN3A2-002
ENSP00000366937
ENST00000377708
P78410 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002456 [T cell mediated immunity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0072643 [interferon-gamma secretion]
Show all
334 aa
36.4 kDa
Yes 1
BTN3A2-003
ENSP00000380152
ENST00000396948
P78410 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002456 [T cell mediated immunity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0072643 [interferon-gamma secretion]
Show all
334 aa
36.4 kDa
Yes 1
BTN3A2-004
ENSP00000432138
ENST00000527422
P78410 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002456 [T cell mediated immunity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0072643 [interferon-gamma secretion]
Show all
334 aa
36.4 kDa
Yes 1
BTN3A2-005
ENSP00000435952
ENST00000532865
E9PRR1 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
196 aa
21.1 kDa
No 0
BTN3A2-006
ENSP00000433749
ENST00000527417
E9PJE9 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
160 aa
17.5 kDa
Yes 0
BTN3A2-008
ENSP00000434102
ENST00000530653
E9PRX1 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
115 aa
12.7 kDa
No 0
BTN3A2-016
ENSP00000474533
ENST00000527639
S4R3N0 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
Show all
115 aa
12.9 kDa
No 1
BTN3A2-201
ENSP00000380140
ENST00000396934
P78410 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002456 [T cell mediated immunity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0072643 [interferon-gamma secretion]
Show all
311 aa
33.9 kDa
No 1
BTN3A2-202
ENSP00000442687
ENST00000508906
P78410 [Direct mapping]
Butyrophilin subfamily 3 member A2
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002456 [T cell mediated immunity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0072643 [interferon-gamma secretion]
Show all
292 aa
32 kDa
No 1

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.