Cell atlas - RPS19BP1 - The Human Protein Atlas

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RPS19BP1

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoli
	Nucleus

Human cell
	Cytosol
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	RPS19BP1
Gene description	Ribosomal protein S19 binding protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli & cytosol. In addition localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (validated), Cytosol (supported)
Additional location	In addition localized to the Nucleus (supported)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA042874
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli & cytosol. In addition localized to the nucleus.

Main location

Nucleoli (validated), Cytosol (supported)

Additional location

Nucleus (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA042874	A-431	Nucleus	Spatial
			Nucleoli	Spatial
			Cytosol	Spatial
	HPA042874	U-2 OS	Nucleoli
	HPA042874	U-2 OS	Cytosol
	HPA042874	U-251 MG	Nucleus	Spatial
			Nucleoli	Spatial
			Cytosol	Spatial

GENE INFORMATION
Gene name	RPS19BP1 (HGNC Symbol)
Synonyms	FLJ21770, MGC52010
Description	Ribosomal protein S19 binding protein 1 (HGNC Symbol)
Entrez gene summary
Chromosome	22
Cytoband	q13.1
Chromosome location (bp)	39529093 - 39532855
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187051 (version 83.38)
Entrez gene	91582
UniProt	Q86WX3 (UniProt - Evidence at protein level)
neXtProt	NX_Q86WX3
Antibodypedia	RPS19BP1 antibodies

PROTEIN BROWSER

RPS19BP1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPS19BP1-001 ENSP00000333948 ENST00000334678	Q86WX3 [Direct mapping] Active regulator of SIRT1 A0A024R1T1 [Target identity:100%; Query identity:100%] Ribosomal protein S19 binding protein 1, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0019899 [enzyme binding] GO:0044822 [poly(A) RNA binding] Show all	136 aa 15.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.