Expression of RPS19BP1 in cancer - Summary

GENERAL INFORMATION
Gene name	RPS19BP1
Gene description	Ribosomal protein S19 binding protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nucleolar and nuclear expression in several tissues, with cytoplasmic expression in some cases.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA042874
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

STAINING SUMMARY

HPA042874

GENE INFORMATION
Gene name	RPS19BP1 (HGNC Symbol)
Synonyms	FLJ21770, MGC52010
Description	Ribosomal protein S19 binding protein 1 (HGNC Symbol)
Entrez gene summary
Chromosome	22
Cytoband	q13.1
Chromosome location (bp)	39529093 - 39532855
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187051 (version 83.38)
Entrez gene	91582
UniProt	Q86WX3 (UniProt - Evidence at protein level)
neXtProt	NX_Q86WX3
Antibodypedia	RPS19BP1 antibodies

PROTEIN BROWSER

RPS19BP1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPS19BP1-001 ENSP00000333948 ENST00000334678	Q86WX3 [Direct mapping] Active regulator of SIRT1 A0A024R1T1 [Target identity:100%; Query identity:100%] Ribosomal protein S19 binding protein 1, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0019899 [enzyme binding] GO:0044822 [poly(A) RNA binding] Show all	136 aa 15.4 kDa	No	0