Cell atlas - CLEC2A - The Human Protein Atlas

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CLEC2A

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Plasma membrane

Human cell
	Plasma Membrane

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GENERAL INFORMATION
Gene name	CLEC2A
Gene description	C-type lectin domain family 2, member A
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the plasma membrane.
RNA cell category	Cell line enriched (U-937)
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA072407
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (U-937) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the plasma membrane.

Main location

Plasma membrane (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA072407	HaCaT	Plasma membrane
	HPA072407	RH-30	Plasma membrane
	HPA072407	U-2 OS	Plasma membrane

GENE INFORMATION
Gene name	CLEC2A (HGNC Symbol)
Synonyms	INPE5792, KACL, PILAR, UNQ5792
Description	C-type lectin domain family 2, member A (HGNC Symbol)
Entrez gene summary	CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).[supplied by OMIM, May 2008]
Chromosome	12
Cytoband	p13.31
Chromosome location (bp)	9898673 - 9932381
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188393 (version 83.38)
Entrez gene	387836
UniProt	Q6UVW9 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UVW9
Antibodypedia	CLEC2A antibodies

PROTEIN BROWSER

CLEC2A-001	CLEC2A-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CLEC2A-001 ENSP00000339732 ENST00000339766	Q6UVW9 [Direct mapping] C-type lectin domain family 2 member A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030246 [carbohydrate binding] GO:0042267 [natural killer cell mediated cytotoxicity] GO:0042803 [protein homodimerization activity] Show all	160 aa 18.6 kDa	No	1
CLEC2A-002 ENSP00000396163 ENST00000455827	Q6UVW9 [Direct mapping] C-type lectin domain family 2 member A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030246 [carbohydrate binding] GO:0042267 [natural killer cell mediated cytotoxicity] GO:0042803 [protein homodimerization activity] Show all	174 aa 20 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.