Cell atlas - ZDHHC9 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ZDHHC9

TISSUE

premium

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Golgi apparatus

Human cell
	Cytosol
	Golgi Apparatus

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	ZDHHC9
Gene description	Zinc finger, DHHC-type containing 9
Protein class	Disease related genes Enzymes Potential drug targets Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the Golgi apparatus. In addition localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (supported)
Additional location	In addition localized to the Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA031814
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the Golgi apparatus. In addition localized to the cytosol.

Main location

Golgi apparatus (supported)

Additional location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA031814	A-431	Golgi apparatus
	HPA031814	A-431	Cytosol
	HPA031814	U-2 OS	No staining
	HPA031814	U-251 MG	No staining

GENE INFORMATION
Gene name	ZDHHC9 (HGNC Symbol)
Synonyms	CGI-89, CXorf11, ZDHHC10, ZNF379, ZNF380
Description	Zinc finger, DHHC-type containing 9 (HGNC Symbol)
Entrez gene summary	This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010]
Chromosome	X
Cytoband	q26.1
Chromosome location (bp)	129803288 - 129843909
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188706 (version 83.38)
Entrez gene	51114
UniProt	Q9Y397 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y397
Antibodypedia	ZDHHC9 antibodies

PROTEIN BROWSER

ZDHHC9-001	ZDHHC9-002	ZDHHC9-004	ZDHHC9-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZDHHC9-001 ENSP00000349689 ENST00000357166	Q9Y397 [Direct mapping] Palmitoyltransferase ZDHHC9 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Show all	GO:0002178 [palmitoyltransferase complex] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005794 [Golgi apparatus] GO:0006612 [protein targeting to membrane] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016409 [palmitoyltransferase activity] GO:0018230 [peptidyl-L-cysteine S-palmitoylation] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] GO:0031228 [intrinsic component of Golgi membrane] GO:0043849 [Ras palmitoyltransferase activity] Show all	364 aa 40.9 kDa	No	4
ZDHHC9-002 ENSP00000406165 ENST00000433917	H0Y6K6 [Direct mapping] Palmitoyltransferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	194 aa 21.5 kDa	No	2
ZDHHC9-004 ENSP00000383991 ENST00000406492	Q5JYE8 [Direct mapping] Palmitoyltransferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	170 aa 19.4 kDa	No	3
ZDHHC9-005 ENSP00000360103 ENST00000371064	Q9Y397 [Direct mapping] Palmitoyltransferase ZDHHC9 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Show all	GO:0002178 [palmitoyltransferase complex] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005794 [Golgi apparatus] GO:0006612 [protein targeting to membrane] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016409 [palmitoyltransferase activity] GO:0018230 [peptidyl-L-cysteine S-palmitoylation] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] GO:0031228 [intrinsic component of Golgi membrane] GO:0043849 [Ras palmitoyltransferase activity] Show all	364 aa 40.9 kDa	No	4

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.